MEDICINAL CHEMISTRY SERVICES
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Lead generation, optimization, profile improvement
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Methodology development, synthesis
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Project & portfolio management, oversight support
At Hager Biosciences, we offer medicinal chemistry and synthetic organic chemistry research solutions to your specific pre-clinical R&D needs. We provide innovative medicinal chemistry support on either a contract-based or risk sharing partnership. Our medicinal chemistry expertise and service products include:
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Lead generation & optimization
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Focused libraries for structure activity relationship (SAR) and structure property relationship (SPR)
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Fragment-based hit expansion and evolution
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Solving specific med chem issues such as ADME properties, solubility, scaffold-hopping, novelization of leads
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Fast follower & back-up candidates
Our customized organic synthesis service model includes:
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Synthetic methodology development - validation
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Synthesis of chemical tags & probes
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Protein-small molecule conjugation projects
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Standards and reference compounds
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Unique & proprietary fragments and discovery platform building blocks
The Hager Biosciences Leadership Team is composed of industry-recognized medicinal chemists with demonstrated track records from big-pharma and biotech R&D organizations. This critical mass enables us to offer a comprehensive med chem portfolio management service and partnership capability. These alliances are designed for flexibility to best meet the clients' needs and are individually customized with full confidentiality and IP-protection to suit your specific project for maximum outcome. Our expertise in drug discovery encompasses numerous drug-target classes including:
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GPCRs
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Ion Channels and Gap Junctions
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Kinases / Phosphatases / Proteases
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Nuclear Hormone Receptors
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Peptides / Peptidomimetics
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Neuropeptides
To learn more about the Hager Biosciences medicinal chemistry support capabilities, please contact us.